While doctors prescribe a lot of different medications as chronic fatigue syndrome treatments, none of them is FDA-approved for the condition. A New Drug Application, however, has been filed for the antiviral/immune regulator Ampligen.
Just as chronic fatigue syndrome (CFS or ME/CFS) affects everyone differently, so do the medications used to treat it. It’s essential that you work closely with your doctor to find what’s right for you. You should be familiar with the side effects of the drugs you’re taking, and let your doctor know about any you may develop. If you’re on more than one medication (prescription or over-the-counter), let your doctor and pharmacist know so you can avoid negative interactions.
http://chronicfatigue.about.com/od/treatingfmscfs/a/cfsdrugs.htm?nl=1